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교수진

교수소개

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Professor
  • 김준섭교수 이미지
    김준섭 교수
    • 직책 교수
    • 전공분야 생화학
    • 연구실 생명관 206호
    • 연락처 Tel : 043-820-5253
      E-mail junskim@ut.ac.kr

▶ 학력

- 2002 - 2005 : 한림대학교 의학과(생화학) 박사

- 2000 - 2002 : 한림대학교 노화생명과학과 석사

- 1993 - 2000 : 강원대학교 농생물학과 학사

▶ 경력

- 2023 – 현재 : 한국교통대학교 교수

- 2019 – 현재 : 한국교통대학교 동물윤리위원회 위원장

- 2018 – 2019 : University of South Alabama, 방문교수.

- 2016 – 2023 : 한국교통대학교 부교수

- 2012 – 2016 : 한국교통대학교 조교수.

- 2009 – 2012 : 한림대학교 의학과, 연구조교수.

- 2005 – 2009 : The Scripps Research Institute, 박사후 연구원.

▶ 연구 업적

[학술저서]

- Regulation of NADPH Oxidases by Rac GTPase. Gary M. Bokoch, Davide Gianni, Jun-Sub Kim and Yu-Ya Kao. Handbook of Cell Signaling (Second edition), Vol 2, Chapter 216.


[학술논문 SCI/E]

◆ 구글 학술검색 :

  https://scholar.google.com/citations?hl=ko&user=9zsJ6E4AAAAJ&view_op=list_works&sortby=pubdate

- Lee, HY., Kim, JS. Cherry fruit anthocyanins cyanidin-3-O-glucoside and cyanidin-3-O-rutinoside protect against blue light-induced cytotoxicity in HaCaT cells. Appl Biol Chem 66, 3 (2023). https://doi.org/10.1186/s13765-023-00767-5

- Ahn KJ, Kim JS. TGF-β1 upregulates Sar1a expression and induces procollagen-I secretion in hypertrophic scarring fibroblasts. Open Med (Wars). 2022 Sep 17;17(1):1473-1482. doi: 10.1515/med-2022-0543. PMID: 36188194; PMCID: PMC9483117.

- Kim JS, Lim SS. LED Light-Induced ROS Differentially Regulates Focal Adhesion Kinase Activity in HaCaT Cell Viability. Curr Issues Mol Biol. 2022 Mar 4;44(3):1235-1246. doi: 10.3390/cimb44030082. PMID: 35723305; PMCID: PMC8947587.

- Jin ES, Kim JY, Yang JM, Kim JS, Min J, Jeon SR, Choi KH, Moon GS, Jeong JH. The Effect of Genetically Modified Lactobacillus plantarum Carrying Bone Morphogenetic Protein 2 Gene on an Ovariectomized Rat. J Korean Neurosurg Soc. 2022 Mar;65(2):204-214. doi: 10.3340/jkns.2021.0098. Epub 2021 Nov 4. PMID: 34727681; PMCID: PMC8918239.

- Jeong K, Murphy JM, Kim JH, Campbell PM, Park H, Rodriguez YAR, Choi CS, Kim JS, Park S, Kim HJ, Scammell JG, Weber DS, Honkanen RE, Schlaepfer DD, Ahn EE, Lim SS. FAK Activation Promotes SMC Dedifferentiation via Increased DNA Methylation in Contractile Genes. Circ Res. 2021 Dec 3;129(12):e215-e233. doi: 10.1161/CIRCRESAHA.121.319066. Epub 2021 Oct 27. PMID: 34702049; PMCID: PMC8639767.

- A Quantitative Method to Measure Low Levels of ROS in Nonphagocytic Cells by Using a Chemiluminescent Imaging System. Kim JS, Jeong K, Murphy JM, Rodriguez YAR, Lim SS. Oxid Med Cell Longev. 2019 Jun 11;2019:1754593. PMID: 31285782 

- Nuclear Focal Adhesion Kinase Controls Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia Through GATA4-Mediated Cyclin D1 Transcription. Jeong K, Kim JH, Murphy JM, Park H, Kim SJ, Rodriguez YAR, Kong H, Choi C, Guan JL, Taylor JM, Lincoln TM, Gerthoffer WT, Kim JS, Ahn EE, Schlaepfer DD, Lim SS. Circ Res. 2019 Jul 5;125(2):152-166. PMID: 31096851

- FAK inhibition reduces metastasis of α4 integrin-expressing melanoma to lymph nodes by targeting lymphatic VCAM-1 expression. Jeong K, Murphy JM, Rodriguez YAR, Kim JS, Ahn EE, Lim SS. Biochem Biophys Res Commun. 2019 Feb 19;509(4):1034-1040. PMID: 30660359

- Involvement of small GTPase RhoA in the regulation of superoxide production in BV2 cells in response to fibrillar Aβ peptides. Moon MY, Kim HJ, Li Y, Kim JG, Jeon YJ, Won HY, Kim JS, Kwon HY, Choi IG, Ro E, Joe EH, Choe M, Kwon HJ, Kim HC, Kim YS, Park JB. Cell Signal. 2013 Sep;25(9):1861-9. PMID: 23707391

- Decreased tissue and serum expression of galectin-7 in patients with hypertrophic scars. Cho SB, Kim JS, Zheng Z, Choi MJ, Choi IG, Oh HS, Ahn KJ. Acta Derm Venereol. 2013 Nov;93(6):669-73. PMID: 23493985 

- Neuregulin induces CTGF expression in hypertrophic scarring fibroblasts. Kim JS, Choi IG, Lee BC, Park JB, Kim JH, Jeong JH, Jeong JH, Seo CH. Mol Cell Biochem. 2012 Jun;365(1-2):181-9. PMID: 22350758

- Ras-related GTPases Rap1 and RhoA collectively induce the phagocytosis of serum-opsonized zymosan particles in macrophages. Kim JG, Moon MY, Kim HJ, Li Y, Song DK, Kim JS, Lee JY, Kim J, Kim SC, Park JB. J Biol Chem. 2012 Feb 10;287(7):5145-55. PMID: 22194606 

- Suppression of scar formation in a murine burn wound model by the application of non-thermal plasma. Dae Hoon Lee, Jae-Ok Lee, Wonju Jeon, Ihn-Geun Choi, Jun-Sub Kim, Je Hoon Jeong, Tae-Cheon Kang, and Cheong Hoon Seo. November 2011, Applied Physics Letters 99(20)

- Neuregulin induces HaCaT keratinocyte migration via Rac1-mediated NADPH-oxidase activation.Kim JS, Bak EJ, Lee BC, Kim YS, Park JB, Choi IG. J Cell Physiol. 2011 Nov;226(11):3014-21. PMID: 21302299

- Anthrax edema toxin inhibits Nox1-mediated formation of reactive oxygen species by colon epithelial cells. Kim JS, Bokoch GM. J Innate Immun. 2009;1(2):145-52. PMID: 20046221 

- Emerging evidence for the importance of phosphorylation in the regulation of NADPH oxidases.Bokoch GM, Diebold B, Kim JS, Gianni D. Antioxid Redox Signal. 2009 Oct;11(10):2429-41. PMID: 19358632 

- Reactive oxygen species regulate a slingshot-cofilin activation pathway. Kim JS, Huang TY, Bokoch GM. Mol Biol Cell. 2009 Jun;20(11):2650-60.

- Regulation of Nox1 activity via protein kinase A-mediated phosphorylation of NoxA1 and 14-3-3 binding. Kim JS, Diebold BA, Babior BM, Knaus UG, Bokoch GM. J Biol Chem. 2007 Nov 30;282(48):34787-800. PMID: 17913709 

- Transforming growth factor-beta1 regulates macrophage migration via RhoA. Kim JS, Kim JG, Moon MY, Jeon CY, Won HY, Kim HJ, Jeon YJ, Seo JY, Kim JI, Kim J, Lee JY, Kim PH, Park JB. Blood. 2006 Sep 15;108(6):1821-9. PMID: 16705092 

- Downstream components of RhoA required for signal pathway of superoxide formation during phagocytosis of serum opsonized zymosans in macrophages. Kim JS, Kim JG, Jeon CY, Won HY, Moon MY, Seo JY, Kim JI, Kim J, Lee JY, Choi SY, Park J, Yoon Park JH, Ha KS, Kim PH, Park JB. Exp Mol Med. 2005 Dec 31;37(6):575-87. PMID: 16391519

- Rho is involved in superoxide formation during phagocytosis of opsonized zymosans. Kim JS, Diebold BA, Kim JI, Kim J, Lee JY, Park JB. J Biol Chem. 2004 May 14;279(20):21589-97. PMID: 14970220 

- Exoenzyme Tat-C3 inhibits association of zymosan particles, phagocytosis, adhesion, and complement binding in macrophage cells. Park J, Kim JS, Jung KC, Lee HJ, Kim JI, Kim J, Lee JY, Park JB, Choi SY. Mol Cells. 2003 Oct 31;16(2):216-23. PMID:  14651264 

- Phagocytosis of serum- and IgG-opsonized zymosan particles induces apoptosis through superoxide but not nitric oxide in macrophage J774A.1. Kim JS, Kwon HY, Choi WH, Jeon CY, Kim JI, Kim J, Lee JY, Kim YS, Park JB. Exp Mol Med. 2003 Jun 30;35(3):211-21. PMID: 12858021

- Nerve growth factor induces proliferation of PC12 cells through Cdc42. Seo JY, Kim JS, Ghang JH, Kang TC, Suh JG, Kim EG, Kim JI, Kim J, Lee JY, Park JB. Neuroreport. 2003 Jul 1;14(9):1277-81. PMID: 12824775

- Phosphorylation of 46-kDa protein of synaptic vesicle membranes is stimulated by GTP and Ca2+/calmodulin. Kim AR, Choi WH, Lee SR, Kim JS, Jeon CY, Kim JI, Kim J, Lee JY, Kim EG, Park JB. Exp Mol Med. 2002 Dec 31;34(6):434-43. PMID:  12526085

- GTP binds to Rab3A in a complex with Ca2+/calmodulin. Park JB, Kim JS, Lee JY, Kim J, Seo JY, Kim AR. Biochem J. 2002 Mar 15;362(Pt 3):651-7. PMID: 11879192 


[연구과제]

- Enterokinase에 의한 전이기전 연구 (한국연구재단)

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- 기능성바이오소재 및 LED를 활용한 생리활성 조절 연구 (한국연구재단-중점연구소)